Selank dosage: chart, reported range and vial math

How to mix a Selank vial

These steps are for the 5 mg vial picked in the chart. Change the size there and the amounts here change with it.

1. Wash your hands. Wipe the stopper of the peptide vial and the water vial with an alcohol swab.
2. Draw 3 mL of bacteriostatic water into a syringe.
3. Push the needle through the stopper of the peptide vial and let the water run slowly down the glass, not straight onto the powder.
4. Swirl the vial gently until the powder is gone. Do not shake it.
5. Write the date and 1.6667 mg/mL on the vial, then put it in the fridge.

What Selank is

Selank is a synthetic seven-amino-acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro), described in the Russian literature as an anti-anxiety drug and as an analog of tuftsin. [1]

Other names: TP-7, selank acetate, Thr-Lys-Pro-Arg-Pro-Gly-Pro.

How it has been given to people: not stated in the abstracts of the human studies found; into the nose (intranasal) in the animal work.

What to know before reading a dose

• No human dose could be verified: none of the human study abstracts gives an amount.
• The route is unverified too. The clinical abstracts do not state it, and one imaging abstract uses the word injection with no detail. It should not be assumed that patients were given Selank into the nose.
• The human studies found are small comparisons with benzodiazepines (60 to 70 patients each) published in one Russian-language journal. PubMed indexes two of them as randomized controlled trials, but their abstracts do not describe randomization or blinding. None is registered on ClinicalTrials.gov.
• Not approved in the US or Canada as of the check date. A 2021 review describes Selank as a poorly studied Russian drug sold to US consumers as a dietary supplement [8].
• A Belgian public health laboratory that identified Selank and Semax in seized products wrote that, to its knowledge, they had not completed any clinical trials, and that they are sold online as powder for injection or in nasal sprays [9].
• Health Canada named Selank among unauthorized injectable peptide drugs seized from an online seller [11].
• FDA compounding status: on the FDA page current as of 2026-04-22, Selank is not in the table of substances now in category 2. It is in a separate list of substances that were in category 2 and were then withdrawn by their nominators [10].

What the evidence shows

Each finding is tagged by the kind of study it comes from. Human trials are listed first.

Side effects and warnings

Reported in human studies or on a label:

• The abstracts give no side-effect figures for Selank itself. In one study, adding Selank to phenazepam reduced the tranquilizer's side effects, such as impaired attention and memory, weakness and sedation. [4]
• An early paper describes Selank as not causing the side effects typical of most anti-anxiety drugs. The abstract gives no data for that statement. [1]
• A 2021 review from US pharmacy faculty calls Selank poorly studied and notes that it is sold to US consumers as a dietary supplement. [8]
• FDA says it lacks important safety information on selank acetate in humans and names immune reactions from aggregation and peptide impurities as possible risks of compounded product. [10]

Selank has no approved label in the US or Canada for this use, so there is no official list of who should not use it, no interaction list and no missed-dose rule.

Storage

Keep an unmixed vial the way its label says. Once it is mixed, keep it in the fridge, do not freeze it, and write the mixing date on the vial.

Selank dosage questions

Sources

Each one was opened on 10 Oct 2026 and matched to the line it supports.

1. Zozulya AA et al. The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity. Bull Exp Biol Med 2001. PubMed 11550013.
2. Zozulia AA et al. [Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]. Zh Nevrol Psikhiatr Im S S Korsakova 2008. PubMed 18454096.
3. Medvedev VE et al. [A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders]. Zh Nevrol Psikhiatr Im S S Korsakova 2014. PubMed 25176261.
4. Medvedev VE et al. [Optimization of the treatment of anxiety disorders with selank]. Zh Nevrol Psikhiatr Im S S Korsakova 2015. PubMed 26356395.
5. Uchakina ON et al. [Immunomodulatory effects of selank in patients with anxiety-asthenic disorders]. Zh Nevrol Psikhiatr Im S S Korsakova 2008. PubMed 18577961.
6. Panikratova YR et al. Functional Connectomic Approach to Studying Selank and Semax Effects. Dokl Biol Sci 2020. PubMed 32342318.
7. Kolomin TA et al. [Transcriptome alteration in hippocampus under the treatment of tuftsin analog Selank]. Zh Vyssh Nerv Deiat Im I P Pavlova 2013. PubMed 24450168.
8. Doyno CR et al. Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank. J Clin Pharmacol 2021. PubMed 34396551.
9. Vanhee C et al. The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind. Drug Test Anal 2020. PubMed 31667971.
10. US Food and Drug Administration Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks 2026. fda.gov.
11. Health Canada Unauthorized injectable peptide drugs seized and sold by Canada Peptide may pose serious health risks 2025. recalls-rappels.canada.ca.
12. Health Canada Health Canada Drug Product Database, active ingredient search: selank 2026. health-products.canada.ca.
13. World Anti-Doping Agency The Prohibited List 2026. wada-ama.org.

Looked for and not found

• No dose amount in any PubMed abstract of a human Selank study, so the doses list is empty. The abstracts give patient numbers and in one case a 14-day course, but no figure in mg or mcg.
• Route in the human studies: not stated in the abstracts. One brain-imaging abstract uses the word injection without more detail [6]; the rat study gave it into the nose [7].
• No human half-life or pharmacokinetic figure. A PubMed search for selank with pharmacokinetics, half-life or bioavailability returned only mouse and laboratory studies.
• No label was retrieved. The Russian state register of medicines needs a captcha to search, so the Russian registration and label dose are not recorded here and the products list is empty.
• No Selank trial registered on ClinicalTrials.gov: a search for selank as the intervention returned only two unrelated brain-stimulation studies.
• Not named on the WADA Prohibited List (page checked 2026-10-10, [13]). The list also has an open class, S0, for substances with no current approval by any governmental health authority for human therapeutic use; whether it applies to this compound was not determined here.

Change log

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