US Not approved, in trials Canada Not authorized
Retatrutide has been given once a week by injection under the skin. The Phase 3 obesity trial used 4 mg, 9 mg or 12 mg a week, and the earlier Phase 2 trial used 1 mg to 12 mg, starting at 2 mg or 4 mg. It is not an approved medicine, so there is no label dose.
Retatrutide dosageWhat it is10 mg vial30 mg vial
US Approved, prescription Canada Authorized, prescription
Tirzepatide is injected under the skin once a week. The US and Canadian labels start at 2.5 mg for 4 weeks, then 5 mg, and allow steps of 2.5 mg no sooner than every 4 weeks, up to a maximum of 15 mg a week. These are the label doses for Mounjaro and Zepbound.
Tirzepatide dosageWhat it is5 mg vial20 mg vial30 mg vial
US Approved, prescription Canada Authorized, prescription
Semaglutide for weight management is injected under the skin once a week. The Wegovy label starts at 0.25 mg and steps up every 4 weeks through 0.5 mg, 1 mg and 1.7 mg to 2.4 mg. The US label now allows up to 7.2 mg a week. Canada's stops at 2.4 mg.
Semaglutide dosageWhat it is2 mg vial5 mg vial
US Not approved, in trials Canada Not authorized
Cagrilintide has been given once a week by injection under the skin in trials. The Phase 2 trial tested 0.3 mg to 4.5 mg a week and the Phase 3 trials used 2.4 mg. It is not approved in the US or Canada, so there is no label dose.
Cagrilintide dosageWhat it is
US Not approved Canada Not authorized
The doses passed around for AOD-9604 are 250 to 500 mcg a day by injection, but no published human trial injected it under the skin. The human trials gave it by mouth or into a vein, and the company behind it reported no weight loss in its largest trial. It is not approved anywhere.
AOD-9604 dosageWhat it is2 mg vial
US Not approved Canada Not authorized
There is no human dose for 5-Amino-1MQ. Every published result comes from cells, mice or rats, and no clinical trial is registered. Sellers suggest 50 to 150 mg a day by mouth, but nothing in people backs that number. It is a small molecule, not a peptide, and it is not approved.
5-Amino-1MQ dosageWhat it is
US Not approved Canada Not authorized
There is no human dose for SLU-PP-332. It has not been given to people in any published or registered study. The lab that made it injected it into mice and reports that it is poorly absorbed by mouth. It is a small molecule, not a peptide, and it is not approved.
SLU-PP-332 dosageWhat it is
US Not approved Canada Not authorized
There is no established dose of HGH Fragment 176-191. No published human study of this fragment was found; the research is in rats, mice and cells. Reports describe 250 to 500 mcg once or twice a day, which is not a label dose. It is not approved in the US or Canada. AOD-9604 is a different compound.
HGH Fragment 176-191 dosageWhat it is2 mg vial