Skip to main content Skip to main content

Peptide Dosages | DosageFacts

Peptide dosage reference for the US and Canada
DOSAGEFACTS

HomeGoalsWeight loss and metabolic

Weight loss and metabolic peptides: dosages and status

8 peptides are filed under weight loss and metabolic. Tirzepatide and Semaglutide have an approved product in the US, so their dose comes from a label. The other 6 have no approved label. Each page says whether its doses come from human trials or are only a reported range.

Last checked 10 Oct 2026

Weight loss and metabolic

Peptides 8

Approved in the US 2

Authorized in Canada 2

Checked 10 Oct 2026

Weight loss and metabolic peptides at a glance

PeptideWhere the doses come fromHow oftenUSCanada
RetatrutideTrial doses, no labelOnce weeklyNot approved, in trialsNot authorized
TirzepatideLabel scheduleOnce weeklyApproved, prescriptionAuthorized, prescription
SemaglutideLabel scheduleOnce weeklyApproved, prescriptionAuthorized, prescription
CagrilintideReported range, not a label doseOnce weeklyNot approved, in trialsNot authorized
AOD-9604Reported range, not a label doseOnce dailyNot approvedNot authorized
5-Amino-1MQNo human doseNot approvedNot authorized
SLU-PP-332No human doseNot approvedNot authorized
HGH Fragment 176-191Reported range, not a label doseOnce or twice dailyNot approvedNot authorized

What is known about each one

Retatrutide

US Not approved, in trials Canada Not authorized

Retatrutide has been given once a week by injection under the skin. The Phase 3 obesity trial used 4 mg, 9 mg or 12 mg a week, and the earlier Phase 2 trial used 1 mg to 12 mg, starting at 2 mg or 4 mg. It is not an approved medicine, so there is no label dose.

Retatrutide dosageWhat it is10 mg vial30 mg vial

Tirzepatide

US Approved, prescription Canada Authorized, prescription

Tirzepatide is injected under the skin once a week. The US and Canadian labels start at 2.5 mg for 4 weeks, then 5 mg, and allow steps of 2.5 mg no sooner than every 4 weeks, up to a maximum of 15 mg a week. These are the label doses for Mounjaro and Zepbound.

Tirzepatide dosageWhat it is5 mg vial20 mg vial30 mg vial

Semaglutide

US Approved, prescription Canada Authorized, prescription

Semaglutide for weight management is injected under the skin once a week. The Wegovy label starts at 0.25 mg and steps up every 4 weeks through 0.5 mg, 1 mg and 1.7 mg to 2.4 mg. The US label now allows up to 7.2 mg a week. Canada's stops at 2.4 mg.

Semaglutide dosageWhat it is2 mg vial5 mg vial

Cagrilintide

US Not approved, in trials Canada Not authorized

Cagrilintide has been given once a week by injection under the skin in trials. The Phase 2 trial tested 0.3 mg to 4.5 mg a week and the Phase 3 trials used 2.4 mg. It is not approved in the US or Canada, so there is no label dose.

Cagrilintide dosageWhat it is

AOD-9604

US Not approved Canada Not authorized

The doses passed around for AOD-9604 are 250 to 500 mcg a day by injection, but no published human trial injected it under the skin. The human trials gave it by mouth or into a vein, and the company behind it reported no weight loss in its largest trial. It is not approved anywhere.

AOD-9604 dosageWhat it is2 mg vial

5-Amino-1MQ

US Not approved Canada Not authorized

There is no human dose for 5-Amino-1MQ. Every published result comes from cells, mice or rats, and no clinical trial is registered. Sellers suggest 50 to 150 mg a day by mouth, but nothing in people backs that number. It is a small molecule, not a peptide, and it is not approved.

5-Amino-1MQ dosageWhat it is

SLU-PP-332

US Not approved Canada Not authorized

There is no human dose for SLU-PP-332. It has not been given to people in any published or registered study. The lab that made it injected it into mice and reports that it is poorly absorbed by mouth. It is a small molecule, not a peptide, and it is not approved.

SLU-PP-332 dosageWhat it is

HGH Fragment 176-191

US Not approved Canada Not authorized

There is no established dose of HGH Fragment 176-191. No published human study of this fragment was found; the research is in rats, mice and cells. Reports describe 250 to 500 mcg once or twice a day, which is not a label dose. It is not approved in the US or Canada. AOD-9604 is a different compound.

HGH Fragment 176-191 dosageWhat it is2 mg vial

Other groups

Healing and recoveryGrowth hormoneLongevityBrain and focusSkin and hairHormonal and sexual healthImmuneBlendsAll dosages A to Z

DosageFacts is an information site. It is not medical advice. Talk to a licensed professional before using any medication.